Anti-Recombinant HMGCR, clone A254

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN301555L.50 50 µl -

7 - 16 business days*

304.00€
E-AN301555L.100 100 µl -

7 - 16 business days*

464.00€
 
3-Hydroxy-3-methylglutaryl-CoA reductase (HMGCR) is a transmembrane glycoprotein of the... more
Product information "Anti-Recombinant HMGCR, clone A254"
3-Hydroxy-3-methylglutaryl-CoA reductase (HMGCR) is a transmembrane glycoprotein of the endoplasmic reticulum. It is the rate-limiting enzyme for cholesterol biosynthesis and non-sterol isoprenoid biosynthesis. Play a key role in cellular cholesterol homeostasis. The activity of HMGCR is regulated by negative feedback, in which cholesterol and other end products of the metabolic pathway inhibit the activity of HMGCR in a multivalent manner. Cholesterol inhibits reductase activity mainly by inhibiting the transcription rate of HMGCR gene. HMGCR is the main target of statins, which are a class of cholesterol-lowering drugs.
Keywords: Anti-HMGCR, Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase, Recombinant HMGCR Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN301555L

Properties

Application: WB, IF, FCM, IP
Antibody Type: Monoclonal
Clone: A254
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Recombinant human HMG-CoA Reductase fragment
MW: 97 kD

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H317
P Phrases: P261, P272, P280, P302+352, P333+313
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-Recombinant HMGCR, clone A254"
Write a review
or to review a product.
Viewed