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NEW
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| E-AN302805L.50 | 50 µl | - | - |
10 - 15 business days* |
171.00€
|
||
| E-AN302805L.100 | 100 µl | - | - |
10 - 15 business days* |
259.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that... more
Product information "Anti-Recombinant eRF3a, clone C212425"
Protein function: GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA (PubMed:15987998, PubMed:19417105, PubMed:2511002, PubMed:27863242). GSPT1/ERF3A mediates ETF1/ERF1 delivery to stop codons: The eRF1-eRF3-GTP complex binds to a stop codon in the ribosomal A-site (PubMed:27863242). GTP hydrolysis by GSPT1/ERF3A induces a conformational change that leads to its dissociation, permitting ETF1/ERF1 to accommodate fully in the A-site (PubMed:16777602, PubMed:27863242). Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (PubMed:24486019). Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes (PubMed:30682371) [The UniProt Consortium]
| Keywords: | Anti-GSPT1, Anti-G1 to S phase transition protein 1 homolog, Anti-Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Recombinant eRF3a Monoclonal Antibody |
| Supplier: | Elabscience |
| Supplier-Nr: | E-AN302805L |
Properties
| Application: | WB, IHC, IF, ELISA |
| Antibody Type: | Monoclonal |
| Clone: | C212425 |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human,mouse |
| Format: | Purified |
Database Information
| KEGG ID : | K03267 | Matching products |
| UniProt ID : | P15170 | Matching products |
| Gene ID : | GeneID 2935 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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