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NEW
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| E-AN303085L.50 | 50 µl | - | - |
10 - 15 business days* |
171.00€
|
||
| E-AN303085L.100 | 100 µl | - | - |
10 - 15 business days* |
259.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin... more
Product information "Anti-Recombinant CD11a, clone C312705"
Protein function: Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R (PubMed:11812992, PubMed:15528364). Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15, the interaction is mediated by ITGAL (PubMed:29100055). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Acts as a platform at the immunological synapse to translate TCR engagement and density of the ITGAL ligand ICAM1 into graded adhesion (PubMed:38195629). Required for generation of common lymphoid progenitor cells in bone marrow, indicating a role in lymphopoiesis (By similarity). Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590) [The UniProt Consortium]
| Keywords: | Anti-ITGAL, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A, Anti-Leukocyte adhesion glycoprotein LFA-1 alpha chain, Anti-Leukocyte function-associated molecule 1 alpha chain, Recombinant CD11a Monoclonal Antibody |
| Supplier: | Elabscience |
| Supplier-Nr: | E-AN303085L |
Properties
| Application: | WB, IHC, ICC/IF, FCM, IP |
| Antibody Type: | Monoclonal |
| Clone: | C312705 |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Format: | Purified |
Database Information
| KEGG ID : | K05718 | Matching products |
| UniProt ID : | P20701 | Matching products |
| Gene ID : | GeneID 3683 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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