Anti-Recombinant AKT1, clone A123

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN301428L.50 50 µl -

7 - 16 business days*

304.00€
E-AN301428L.100 100 µl -

7 - 16 business days*

464.00€
 
The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and... more
Product information "Anti-Recombinant AKT1, clone A123"
The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
Keywords: Anti-AKT1, Anti-RAC-PK-alpha, Anti-Protein kinase B, Anti-Proto-oncogene c-Akt, Anti-Protein kinase B alpha, Anti-RAC-alpha serine/threonine-protein kinase, Recombinant AKT1 Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN301428L

Properties

Application: WB, IHC
Antibody Type: Monoclonal
Clone: A123
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse
Immunogen: Recombinant human AKT1 fragment
MW: 60 kD

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H317
P Phrases: P261, P272, P280, P302+352, P333+313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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