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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG58166.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
Protein function: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP... more
Product information "Anti-RCC1"
Protein function: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double- stranded DNA (PubMed:17435751, PubMed:18762580). [The UniProt Consortium]
Keywords: | Anti-CHC1, Anti-RCC1, Anti-Cell cycle regulatory protein, Anti-Chromosome condensation protein 1, Anti-Regulator of chromosome condensation |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG58166 |
Properties
Application: | IHC (paraffin), WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant funsion protein corresponding to aa. 1-240 of Human RCC1 (NP_001260.1) |
MW: | 45 kD |
Format: | Affinity Purified |
Database Information
KEGG ID : | K11493 | Matching products |
UniProt ID : | P18754 | Matching products |
Gene ID | GeneID 1104 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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