Anti-RCC1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG58166.100 100 µl - -

6 - 14 business days*

624.00€
 
Protein function: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP... more
Product information "Anti-RCC1"
Protein function: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double- stranded DNA (PubMed:17435751, PubMed:18762580). [The UniProt Consortium]
Keywords: Anti-CHC1, Anti-RCC1, Anti-Cell cycle regulatory protein, Anti-Chromosome condensation protein 1, Anti-Regulator of chromosome condensation
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG58166

Properties

Application: IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant funsion protein corresponding to aa. 1-240 of Human RCC1 (NP_001260.1)
MW: 45 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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