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Protein function: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP... more
Product information "Anti-RCC1"
Protein function: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly. [The UniProt Consortium]
Keywords: | Anti-CHC1, Anti-RCC1, Anti-Cell cycle regulatory protein, Anti-Chromosome condensation protein 1, Anti-Regulator of chromosome condensation |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A302-605A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Reactivity: | Human (Expected: Golden Hamster) |
Immunogen: | synthetic peptide. The epitope recognized by A302-605A-T maps to a region between residue 371 and 421 of human regulator of chromosome condensation 1 using the numbering given in entry NP_001260.1 (GeneID 1104 ). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K11493 | Find alternatives |
UniProt ID : | P18754 | Find alternatives |
Gene ID | GeneID 1104 | Find alternatives |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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