Anti-RAPGEF3 Recombinant

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-RC-5303.50	50 µl		-	-	Request delivery time estimate		206.00€
ABS-RC-5303.100	100 µl		-	-	Request delivery time estimate		295.00€

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Protein function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that... more

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Product information "Anti-RAPGEF3 Recombinant"

Protein function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP- induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin. [The UniProt Consortium]

Keywords:	Anti-Rap guanine nucleotide exchange factor 3, Anti-Exchange factor directly activated by cAMP 1, Anti-Exchange protein directly activated by cAMP 1, Anti-EPAC 1, Anti-Rap1 guanine-nucleotide-exchange factor directly activated by cAMP, Anti-cAMP-regulated
Supplier:	Absea
Supplier-Nr:	RC-5303

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	1Q83
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Format:	Solution

Database Information

KEGG ID :	K08014 \| Matching products
UniProt ID :	O95398 \| Matching products
Gene ID :	GeneID 10411 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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