- Search results for K08014
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
18 products were found matching "K08014"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay17143-1
Exchange proteins activated by cAMP (Epacs) are guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-pCPT-2'-O-methyl Cyclic AMP (8-pCPT-2'-O-Me-cAMP) is an 8-(4-chlorophenylthio) analog of cAMP that activates Epacs (AC50 = 1.8 µM). It is a super-activator of Epacs in that it dissociates...
Keywords: | 8-CPT-2Me-cAMP, 8-pCPT-cAMP, 8-pCPT-2'-O-Me-cAMP, 8-[(4-chlorophenyl)thio]-2'-O-methyl-adenosine cyclic 3',5'-(hydrogen... |
Application: | EPAC activator |
CAS | 634207-53-7 |
MW: | 507.8 D |
From 152.00€
*
Item number: Cay17767-5
Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). CE3F4 is an uncompetitive inhibitor of Epac1 activity toward its effector Rap1 in vitro (IC50 = 23 µM) and in cells.. It has no effect on PKA activity. CE3F4 blocks Epac1-induced autophagy in...
Keywords: | 5,7-dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde |
Application: | Epac1 inhibitor |
CAS | 143703-25-7 |
MW: | 351 D |
From 105.00€
*
Item number: Cay19130-10
Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). ESI-09 is an inhibitor of Epac1 and Epac2 with IC50 values of 3.2 and 1.4 µM, respectively. It shows no activity against PKA at concentrations as high as 25 µM. ESI-09 has been shown to block Akt...
Keywords: | alpha-[2-(3-chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-beta-oxo-3-isoxazolepropanenitrile |
Application: | Epac1 / Epac2 inhibitor |
CAS | 263707-16-0 |
MW: | 330.8 D |
From 43.00€
*
Item number: Cay19092-1
Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). HJC0197 is a cell-permeable inhibitor of Epac1 and Epac2 (IC50 = 5.9 µM for Epac2). It inhibits Epac1-mediated Rap1-GDP exchange activity at 25 µM, but has no effect on cAMP-induced type I and II PKA...
Keywords: | 4-cyclopentyl-2-[[(2,5-dimethylphenyl)methyl]thio]-1,6-dihydro-6-oxo-5-pyrimidinecarbonitrile |
Application: | Cell-permeable Epac1 / Epac2 inhibitor |
CAS | 1383539-73-8 |
MW: | 339.5 D |
From 50.00€
*
Item number: NSJ-RQ4808
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs. The Epac signaling therefore represents a novel mechanism for cAMP...
Keywords: | Anti-CGEF1, Anti-EPAC 1, Anti-RAPGEF3, Anti-cAMP-GEFI, Anti-Rap guanine nucleotide exchange factor 3, Anti-Exchange factor... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
755.00€
*
Item number: ATA-HPA040365.100
Protein function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a...
Keywords: | Anti-CGEF1, Anti-EPAC 1, Anti-RAPGEF3, Anti-cAMP-GEFI, Anti-Rap guanine nucleotide exchange factor 3, Anti-Exchange factor... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 300.00€
*
Item number: ATA-HPA043518.100
Protein function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a...
Keywords: | Anti-CGEF1, Anti-EPAC 1, Anti-RAPGEF3, Anti-cAMP-GEFI, Anti-Rap guanine nucleotide exchange factor 3, Anti-Exchange factor... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 300.00€
*
Item number: NSJ-RQ6703
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Rap guanine nucleotide exchange factor 3 also known as exchange factor directly activated by cAMP 1 (EPAC1) or cAMP-regulated guanine nucleotide exchange factor I (cAMP-GEFI) is a protein that in humans is encoded by the RAPGEF3 gene. As the name suggests, EPAC...
Keywords: | Anti-CGEF1, Anti-EPAC 1, Anti-RAPGEF3, Anti-cAMP-GEFI, Anti-Rap guanine nucleotide exchange factor 3, Anti-Exchange factor... |
Application: | WB, IHC (paraffin), IF, FC, Direct ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, monkey |
755.00€
*
Item number: ELK-ES4469.100
caution:It is uncertain whether Met-1 or Met-43 is the initiator.,domain:The DEP domain is involved in membrane localization independent from regulation by cAMP.,function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP.,similarity:Contains 1 cyclic...
Keywords: | Anti-CGEF1, Anti-EPAC 1, Anti-RAPGEF3, Anti-cAMP-GEFI, Anti-Rap guanine nucleotide exchange factor 3, Anti-Exchange factor... |
Application: | WB, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 169.00€
*
Item number: 600-401-BB1
Anti-EPAC1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of EPAC1 are known to exist, this antibody will detect both isoforms. EPAC1 antibody is predicted to not cross-react with EPAC2. Protein function: Guanine nucleotide exchange factor (GEF) for...
Keywords: | Anti-CGEF1, Anti-EPAC 1, Anti-RAPGEF3, Anti-cAMP-GEFI, Anti-Rap guanine nucleotide exchange factor 3, Anti-Exchange factor... |
Application: | ELISA, IHC, IFM, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
684.00€
*
Item number: VHPS-3001
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | Putative uncharacterized protein |
Application: | RNA quantification |
43.00€
*
Item number: VHPS-4377
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | Putative uncharacterized protein |
Application: | RNA quantification |
43.00€
*