Anti-RAPGEF3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA043518.25	25 µl		-		7 - 10 business days*		320.00€
ATA-HPA043518.100	100 µl		-		7 - 10 business days*		450.00€

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Protein function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that... more

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Product information "Anti-RAPGEF3"

Protein function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP- induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 82% and to rat: 81%

Keywords:	Anti-CGEF1, Anti-EPAC 1, Anti-RAPGEF3, Anti-cAMP-GEFI, Anti-Rap guanine nucleotide exchange factor 3, Anti-Exchange factor directly activated by cAMP 1, Anti-Exchange protein directly activated by cAMP 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA043518

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TYVCNKRQQI LRLVSQWVAL YGSMLHTDPV ATSFLQKLSD LVGRDTRLSN LLREQWPERR RCHRLENGCG NASPQMKARN LPVWLPNQDE PLPGSSCAIQ (ATA-APrEST80958)