Anti-RAB25

Anti-RAB25
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES20248.50 50 µl - -

10 - 14 business days*

169.00€
ELK-ES20248.100 100 µl - -

10 - 14 business days*

283.00€
 
The protein encoded by this gene is a member of the RAS superfamily of small GTPases. The encoded... more
Product information "Anti-RAB25"
The protein encoded by this gene is a member of the RAS superfamily of small GTPases. The encoded protein is involved in membrane trafficking and cell survival. This gene has been found to be a tumor suppressor and an oncogene, depending on the context. Two variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Nov 2015], Protein function: Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia (PubMed:17925226). Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions. May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000. Cellular localization: Cell membrane , Lipid-anchor , Cytoplasmic side . Cell projection, pseudopodium membrane . Cytoplasmic vesicle . Colocalizes with integrin alpha-V/beta-1 in vesicles at the pseudopodial tips. .
Keywords: Anti-CATX8, Anti-CATX-8, Anti-Ras-related protein Rab-25, RAB25 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES20248

Properties

Application: WB, ELISA, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse,
Immunogen: Synthesized peptide derived from human RAB25 AA range: 80-160
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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