Anti-PTPRR

Anti-PTPRR
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-65872.60 60 µl -

7 - 16 business days*

198.00€
E-AB-65872.120 120 µl -

7 - 16 business days*

317.00€
E-AB-65872.200 200 µl -

7 - 16 business days*

525.00€
 
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.... more
Product information "Anti-PTPRR"
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. Protein function: Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. [The UniProt Consortium]
Keywords: Anti-ECPTP, Anti-PTPRR, Anti-R-PTP-R, Anti-NC-PTPCOM1, Anti-Ch-1PTPase, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase PCPTP1, Anti-Receptor-type tyrosine-protein phosphatase R, PTPRR Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-65872

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: mouse
Immunogen: Recombinant fusion protein of human PTPRR (NP_002840.2).

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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