Protein function: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426). [The UniProt Consortium]
synthetic peptide. The epitope recognized by A301-544A-T maps to a region between residue 543 and 593 of human tyrosine-protein phosphatase non-receptor type 11 using the numbering given in entry NP_002825.3 (GeneID 5781).