Anti-PPP6C

Anti-PPP6C
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-844A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A300-844A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a... more
Product information "Anti-PPP6C"
Protein function: Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. Participates also in the innate immune defense against viruses by desphosphorylating RIG-I/DDX58, an essential step that triggers RIG-I/DDX58-mediated signaling activation. [The UniProt Consortium]
Keywords: Anti-PPP6, Anti-PPP6C, EC=3.1.3.16
Supplier: Bethyl Laboratories
Supplier-Nr: A300-844A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat)
Immunogen: synthetic peptide. The epitope recognized by A300-844A-T maps to a region between residue 250 and the C-terminus (residue 305) of human Protein Phosphatase 6, Catalytic Subunit using the numbering given in entry NP_002712.1 (GeneID 5537).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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