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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R31377 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Paraoxonase 1, also known as Aromatic... more
Product information "Anti-PON1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Paraoxonase 1, also known as Aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. This protein has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the gene significantly affect the catalytic ability of the enzyme. Paraoxonase 1 is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The gene is activated by PPAR-gamma, which increases synthesis and release of PON1 enzyme from the liver, reducing atherosclerosis. Protein function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. [The UniProt Consortium]
Keywords: | Anti-PON, Anti-K-45, Anti-PON1, Anti-PON 1, Anti-A-esterase 1, Anti-Aromatic esterase 1, Anti-Serum aryldialkylphosphatase 1, Anti-Serum paraoxonase/arylesterase 1, PON1 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R31377 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Amino acid sequence from the middle region of human Paraoxonase 1 (FLDPYLQSWEMYLGLA) |
Format: | Purified |
Database Information
KEGG ID : | K01045 | Matching products |
UniProt ID : | P27169 | Matching products |
Gene ID | GeneID 5444 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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