Anti-Piwi-like Protein 2 (Mili, Piwil2)

Mili, otherwise known as Piwi-like protein 2, is an Argonaute protein, a member of the 'Piwi family.' It is required for germ cell and stem cell development in invertebrates. Mili is essential for spermatogenesis in mouse and plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. It is also essential for meiotic differentiation and self-renewal of spermatogonial stem cells. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 2-4ug/ml, Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.