Protein function: Endoribonuclease that plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity (PubMed:11578866, PubMed:14736746, PubMed:17446352, PubMed:18381894, PubMed:18922463, PubMed:26669262). Plays an...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Mili, otherwise known as Piwi-like protein 2, is an Argonaute protein, a member of the 'Piwi family.' It is required for germ cell and stem cell development in invertebrates. Mili is essential for spermatogenesis in mouse and plays a central role during spermatogenesis by repressing transposable elements and...