Anti-PIP4K2B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA047875.25	25 µl		-		7 - 10 business days*		358.00€
ATA-HPA047875.100	100 µl		-		7 - 10 business days*		477.00€

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Protein function: Participates in the biosynthesis of phosphatidylinositol 4,5- bisphosphate... more

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Product information "Anti-PIP4K2B"

Protein function: Participates in the biosynthesis of phosphatidylinositol 4,5- bisphosphate (PubMed:9038203, PubMed:26774281). Preferentially utilizes GTP, rather than ATP, for PI(5)P phosphorylation and its activity reflects changes in direct proportion to the physiological GTP concentration (PubMed:26774281). Its GTP-sensing activity is critical for metabolic adaptation (PubMed:26774281). PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3 (PubMed:31091439). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 88%

Keywords:	Anti-PIP5K2B, Anti-PIP4KII-beta, Anti-PI(5)P 4-kinase type II beta, Anti-Diphosphoinositide kinase 2-beta, Anti-PtdIns(5)P-4-kinase isoform 2-beta, Anti-1-phosphatidylinositol 5-phosphate 4-kinase 2-beta
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA047875

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EERAEDEECE NDGVGGNLLC SYGTPP (ATA-APrEST84386)