71 products were found matching "K00920"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. PIP4K2B antibody detects Phosphatidylinositol-5-phosphate 4-kinase type-2 beta, a lipid kinase involved in the generation of phosphatidylinositol-4,5-bisphosphate (PIP2), a key signaling molecule regulating membrane trafficking, cytoskeletal...

BAY-091 is an inhibitor of phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A, IC50 = 1 nM). InChI: InChI=1S/C26H21FN4O2/c1-3-21(26(32)33)30-25-19-11-12-29-14-22(19)31-24(20(25)13-28)17-9-7-16(8-10-17)18-6-4-5-15(2)23(18)27/h4-12,14,21H,3H2,1-2H3,(H,30,31)(H,32,33)/t21-/m1/s1 InChIKey:...

Protein function: Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT...

Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of...

Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of...

NIH 12848 is an inhibitor of phosphatidylinositol 5-phosphate 4-kinase gamma (PI5P4Kgamma, IC50 = ~1 µM). It is selective for PI5P4Kgamma over PI5P4Kalpha and PI5P4Kbeta (IC50s = >100 µM). NIH 12848 inhibits translocation of the Na+/K+-ATPase to the plasma membrane in mouse principal kidney cortical collecting duct...

Protein function: Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT...

Protein function: Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. [The UniProt Consortium]

PIP4K2C Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, IHC, IF applications. PIP4K2C Antibody is a high quality polyclonal antibody for research use only.. Protein function: Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP...

Protein function: Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress...

Protein function: Participates in the biosynthesis of phosphatidylinositol 4,5- bisphosphate (PubMed:9038203, PubMed:26774281). Preferentially utilizes GTP, rather than ATP, for PI(5)P phosphorylation and its activity reflects changes in direct proportion to the physiological GTP concentration (PubMed:26774281). Its...