Anti-PIP4K2B

Anti-PIP4K2B
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-KC-32085.50 50 µl - -

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206.00€
ABS-KC-32085.100 100 µl - -

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295.00€
 
Protein function: Participates in the biosynthesis of phosphatidylinositol 4,5- bisphosphate... more
Product information "Anti-PIP4K2B"
Protein function: Participates in the biosynthesis of phosphatidylinositol 4,5- bisphosphate (PubMed:9038203, PubMed:26774281). Preferentially utilizes GTP, rather than ATP, for PI(5)P phosphorylation and its activity reflects changes in direct proportion to the physiological GTP concentration (PubMed:26774281). Its GTP-sensing activity is critical for metabolic adaptation (PubMed:26774281). PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3 (PubMed:31091439). [The UniProt Consortium]
Keywords: Anti-PIP5K2B, Anti-PIP4KII-beta, Anti-PI(5)P 4-kinase type II beta, Anti-Diphosphoinositide kinase 2-beta, Anti-PtdIns(5)P-4-kinase isoform 2-beta, Anti-1-phosphatidylinositol 5-phosphate 4-kinase 2-beta
Supplier: Absea
Supplier-Nr: KC-32085

Properties

Application: WB
Antibody Type: Monoclonal
Clone: K24077_20A7
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: recombinant human PIP4K2B
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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