Anti-Phospho-SMO-S616 [Rabbit] (CABP0938)

Phospho-SMO-S616 Rabbit Polyclonal Antibody from Assay Genie with reactivity against Human and for use in WB applications.Phospho-SMO-S616 Rabbit Polyclonal Antibody is an IgG isotype antibody and produced in Rabbit and purified by Affinity purification from Assay Genie.. Protein function: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia (PubMed:19592253). Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation. [The UniProt Consortium]