Anti-PHLPP2, clone SP220

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG53458.100	100 µl		-	-	6 - 14 business days*		608.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1,... more

Close menu

Product information "Anti-PHLPP2, clone SP220"

Protein function: Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor. [The UniProt Consortium]

Keywords:	Anti-PHLPP2, Anti-KIAA0931, Anti-PHLPP-like, EC=3.1.3.16, Anti-PH domain leucine-rich repeat-containing protein phosphatase 2, Anti-PH domain leucine-rich repeat-containing protein phosphatase-like
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG53458

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Monoclonal
Clone:	SP220
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide derived from human PHLPP2 protein
Format:	Liquid