Anti-PHLPP2, C-terminal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG64267.100	100 µg		-	-	6 - 14 business days*		784.00€

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Protein function: Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1,... more

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Product information "Anti-PHLPP2, C-terminal"

Protein function: Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor. [The UniProt Consortium]

Keywords:	Anti-PHLPP2, Anti-KIAA0931, Anti-PHLPP-like, EC=3.1.3.16, Anti-PH domain leucine-rich repeat-containing protein phosphatase 2, Anti-PH domain leucine-rich repeat-containing protein phosphatase-like
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG64267

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human
Immunogen:	C-PHEEDRTEPPEEFD
Format:	Ammonium Sulfate Precipitated