Anti-PGP9.5 (UchL1), clone UCHL1/775

Anti-PGP9.5 (UchL1), clone UCHL1/775
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2920-20UG 20 µg - -

3 - 10 business days

NSJ-V2920-100UG 100 µg - -

3 - 10 business days

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This mAb reacts with a protein of... more
Product information "Anti-PGP9.5 (UchL1), clone UCHL1/775"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This mAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease. Protein function: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. [The UniProt Consortium]
Keywords: Anti-UCHL1, Anti-UCH-L1, Anti-PGP9.5, Anti-PGP 9.5, EC=6.-.-.-, EC=, Anti-Ubiquitin thioesterase L1, Anti-Neuron cytoplasmic protein 9.5, Anti-Ubiquitin carboxyl-terminal hydrolase isozyme L1, PGP9.5 Antibody (UchL1)
Supplier: NSJ Bioreagents
Supplier-Nr: V2920-20UG


Application: WB, IHC (paraffin)
Antibody Type: Monoclonal
Clone: UCHL1/775
Conjugate: No
Host: Mouse
Reactivity: Human, Rat (Expected: Broad)
Immunogen: Recombinant human UCHL1 protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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