Anti-PEA-15

Anti-PEA-15
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES7856.50 50 µl - -

10 - 14 business days*

169.00€
ELK-ES7856.100 100 µl - -

10 - 14 business days*

283.00€
 
phosphoprotein enriched in astrocytes 15(PEA15) Homo sapiens This gene encodes a death effector... more
Product information "Anti-PEA-15"
phosphoprotein enriched in astrocytes 15(PEA15) Homo sapiens This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014], Protein function: Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: Cytoplasm. Associated with microtubules.
Keywords: Anti-PED, Anti-PEA15, Anti-Astrocytic phosphoprotein PEA-15, Anti-Phosphoprotein enriched in diabetes, Anti-15 kDa phosphoprotein enriched in astrocytes, PEA-15 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES7856

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat, monkey
Immunogen: The antiserum was produced against synthesized peptide derived from human PEA-15. AA range:81-130
MW: 36 kD
Format: Antiserum

Database Information

UniProt ID : Q15121 | Matching products
Gene ID : GeneID 8682 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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