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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V2812SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
1 mg/ml in sterile PBS, BSA free, sodium azide free. Epitope of this mAb maps in the C-terminus... more
Product information "Anti-Parathyroid Hormone Cocktail (N + C Terminal), clone 3H9 + PTH/1175"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Epitope of this mAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Protein function: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. [The UniProt Consortium]
Keywords: | Anti-PTH, Anti-Parathyrin, Anti-Parathormone, Anti-Parathyroid hormone, Parathyroid Hormone Antibody Cocktail (N + C Terminal) |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V2812SAF |
Properties
Application: | FC, IF, IHC (paraffin) |
Antibody Type: | Mixed |
Clone: | 3H9+PTH/1175 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Amino acids 1-34 of human PTH (3H9), An 84 amino acid partial recombinant from C-terminus human PTH protein (PTH/1175) |
Format: | Purified |
Database Information
KEGG ID : | K05261 | Matching products |
UniProt ID : | P01270 | Matching products |
Gene ID | GeneID 5741 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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