Anti-Parathyroid Hormone Cocktail (N + C Terminal), clone 3H9 + PTH/1175

Anti-Parathyroid Hormone Cocktail (N + C Terminal), clone 3H9 + PTH/1175
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2812-20UG 20 µg - -

3 - 10 business days*

332.00€
NSJ-V2812-100UG 100 µg - -

3 - 10 business days*

752.00€
 
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Epitope of this mAb maps in the... more
Product information "Anti-Parathyroid Hormone Cocktail (N + C Terminal), clone 3H9 + PTH/1175"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Epitope of this mAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Protein function: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. [The UniProt Consortium]
Keywords: Anti-PTH, Anti-Parathyrin, Anti-Parathormone, Anti-Parathyroid hormone, Parathyroid Hormone Antibody Cocktail (N + C Terminal)
Supplier: NSJ Bioreagents
Supplier-Nr: V2812

Properties

Application: FC, IF, IHC (paraffin)
Antibody Type: Mixed
Clone: 3H9+PTH/1175
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Amino acids 1-34 of human PTH (3H9), An 84 amino acid partial recombinant from C-terminus human PTH protein (PTH/1175)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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