Anti-NUDT1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA012636.25 25 µl -

7 - 10 business days*

369.00€
ATA-HPA012636.100 100 µl -

7 - 10 business days*

491.00€
 
Protein function: Antimutagenic (PubMed:8226881, PubMed:7713500, PubMed:10608900). Plays a... more
Product information "Anti-NUDT1"
Protein function: Antimutagenic (PubMed:8226881, PubMed:7713500, PubMed:10608900). Plays a redundant role in sanitizing oxidized nucleotide pools, such as 8-oxo-dGTP pools (PubMed:28679043). Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress (PubMed:12857738, PubMed:24695224, PubMed:24695225). Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions (PubMed:8226881, PubMed:10373420, PubMed:10608900, PubMed:11756418, PubMed:12857738, PubMed:16607562, PubMed:24695224, PubMed:24695225, PubMed:26999531, PubMed:28035004). Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8- oxo-GTP and 8-oxo-ATP (PubMed:10373420, PubMed:11139615). Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 81% and to rat: 83%
Keywords: Anti-NUDT1, Anti-8-oxo-dGTPase, Anti-Nudix motif 1, Anti-2-hydroxy-dATP diphosphatase, Anti-7,8-dihydro-8-oxoguanine triphosphatase, Anti-Nucleoside diphosphate-linked moiety X motif 1
Supplier: Atlas Antibodies
Supplier-Nr: HPA012636

Properties

Application: ICC, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: RWNGFGGKVQ EGETIEDGAR RELQEESGLT VDALHKVGQI VFEFVGEPEL MDVHVFCTDS IQGTPVESDE MRPCWFQLDQ IPFKDMWPDD SYWFPLLLQK KKFHGYFKFQ GQDTILDYTL (ATA-APrEST71059)

Database Information

KEGG ID : K17816 | Matching products
UniProt ID : P36639 | Matching products
Gene ID : GeneID 4521 | Matching products
Protein Atlas Nr. : ENSG00000106268

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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