Anti-NOTCH4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F53420-0.08ML	80 µl		-	-	3 - 10 business days*		326.00€
NSJ-F53420-0.4ML	400 µl		-	-	3 - 10 business days*		702.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. Functions as a receptor for membrane-bound ligands... more

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Product information "Anti-NOTCH4"

In 1X PBS, pH 7.4, with 0.09% sodium azide. Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity). Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system. [The UniProt Consortium]

Keywords:	Anti-INT3, Anti-NOTCH4, NOTCH4 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	F53420

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	This NOTCH4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1819-1851 amino acids from the C-terminal region of human NOTCH4.
Format:	Purified