Anti-NOD2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
200-401-DC8	100 µg		-	-	6 - 10 business days*		848.00€

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Anti-NOD2 Antibody was Protein A purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-NOD2"

Anti-NOD2 Antibody was Protein A purified from monospecific antiserum by immunoaffinity purification. NOD2 has no cross-reaction with NOD1. Protein function: Recognizes muramyl dipeptide (MDP) constituents of bacterial peptidoglycans and plays a key role in gastrointestinal immunity: upon stimulation, binds the proximal adapter receptor- interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling, leading to activate the transcription of hundreds of genes involved in immune response. [The UniProt Consortium]

Keywords:	Anti-NOD2, Anti-CARD15, Anti-Inflammatory bowel disease protein 1, Anti-Caspase recruitment domain-containing protein 15, Anti-Nucleotide-binding oligomerization domain-containing protein 2
Supplier:	Rockland Immunochemicals
Supplier-Nr:	200-401-DC8

Properties

Application:	ELISA, IHC, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide corresponding to 16 amino acids at the N-terminus of human NOD2.
Format:	Purified