Anti-NMDAR2B, clone S59-36

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG22230.50	50 µg		-	-	6 - 14 business days*		584.00€

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Protein function: NMDA receptor subtype of glutamate-gated ion channels with high calcium... more

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Product information "Anti-NMDAR2B, clone S59-36"

Protein function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death. [The UniProt Consortium]

Keywords:	Anti-NR2B, Anti-Grin2b, Anti-GluN2B, Anti-NMDAR2B, Anti-Glutamate receptor ionotropic, NMDA 2B, Anti-N-methyl D-aspartate receptor subtype 2B, Anti-Glutamate [NMDA] receptor subunit epsilon-2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG22230

Properties

Application:	WB, IHC, ICC, IF, IP
Antibody Type:	Monoclonal
Clone:	S59-36
Conjugate:	No
Host:	Mouse
Species reactivity:	human, mouse, rat
Immunogen:	Fusion protein around aa. 20-271 (extracellular N-terminus) of Rat NMDAR2B
MW:	166 kD
Format:	Purified