Anti-NMDAR2B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-P64	100 µg		-	-	6 - 10 business days*		641.00€

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Anti-NMDAR2B antibody is directed against human NMDAR2B protein. The product was affinity... more

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Product information "Anti-NMDAR2B"

Anti-NMDAR2B antibody is directed against human NMDAR2B protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human, mouse, and rat based on 100% homology for the immunogen sequence. Cross reactivity with NMDAR2B from other sources has not been determined. Protein function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death. [The UniProt Consortium]

Keywords:	Anti-NR3, Anti-NR2B, Anti-hNR3, Anti-GRIN2B, Anti-GluN2B, Anti-NMDAR2B, Anti-Glutamate receptor ionotropic, Anti-NMDA 2B, Anti-N-methyl-D-aspartate receptor subunit 3, Anti-N-methyl D-aspartate receptor subtype 2B, Anti-Glutamate [NMDA] receptor subunit e
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-P64

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide corresponding to a sequence at the C-terminal of human NMDAR2B.
Format:	Purified