Anti-Nicastrin Recombinant

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-RC-6996.50	50 µl		-	-	10 - 15 business days*		206.00€
ABS-RC-6996.100	100 µl		-	-	10 - 15 business days*		295.00€

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Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that... more

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Product information "Anti-Nicastrin Recombinant"

Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546, PubMed:30630874). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. [The UniProt Consortium]

Keywords:	Anti-Nicastrin, Recombinant NCSTN Antibody
Supplier:	Absea
Supplier-Nr:	RC-6996

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	3L51
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Format:	Solution

Database Information

KEGG ID :	K06171 \| Matching products
UniProt ID :	Q92542 \| Matching products
Gene ID :	GeneID 23385 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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