30 products were found matching "K06171"!

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Anti-Nicastrin
Anti-Nicastrin

Item number: A304-464A

Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335). The gamma-...
Keywords: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Application: WB, IP
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-Nicastrin
Anti-Nicastrin

Item number: 600-401-DB1

Anti-Nicastrin Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Nicastrin from other sources has not been determined. Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage...
Keywords: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Application: ELISA, IHC, IFM, WB
Host: Rabbit
Species reactivity: human, mouse, rat
684.00€ *
Review
Anti-Nicastrin
Anti-Nicastrin

Item number: 600-401-DB2

Anti-Nicastrin Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Nicastrin from other sources has not been determined. Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage...
Keywords: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Application: ELISA, IHC, IFM, WB
Host: Rabbit
Species reactivity: human, mouse, rat
684.00€ *
Review
Anti-Nicastrin
Anti-Nicastrin

Item number: NSJ-R31374

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nicastrin, also known as NCSTN, is aproteinthat is a part of the gamma secretase protein complex. It is mapped to 1q23.2. This gene is not catalytically active, but instead promotes the maturation and proper trafficking of the other proteins in the gamma...
Keywords: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, Nicastrin Antibody
Application: WB
Host: Rabbit
Species reactivity: human
755.00€ *
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Anti-NCSTN
Anti-NCSTN

Item number: E-AB-11441.120

This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex...
Keywords: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, NCSTN Polyclonal Antibody
Application: WB, IHC, ELISA
Host: Rabbit
Species reactivity: human, mouse, rat
From 71.00€ *
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Anti-NCSTN
Anti-NCSTN

Item number: E-AB-15254.120

This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex...
Keywords: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, NCSTN Polyclonal Antibody
Application: IHC, ELISA
Host: Rabbit
Species reactivity: human, mouse, rat
From 71.00€ *
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MK-0752
MK-0752

Item number: Cay16706-5

gamma-Secretase is a protease complex that cleaves single-pass transmembrane proteins, such as Notch receptors and beta-amyloid precursor protein (APP), within the transmembrane domain. MK-0752 is a potent, reversible inhibitor of gamma-secretase, reducing the cleavage of APP to Abeta40 in human neuroblastoma...
Keywords: cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)-cyclohexanepropanoic acid
Application: gamma-secretase inhibitor
CAS 471905-41-6
MW: 442.9 D
From 92.00€ *
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Anti-NCSTN / Nicastrin
Anti-NCSTN / Nicastrin

Item number: ARG40091.100

Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546,...
Keywords: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Application: WB
Host: Rabbit
Species reactivity: mouse, rat
624.00€ *
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Anti-NCSTN
Anti-NCSTN

Item number: G-CAB0128.100

Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 352.00€ *
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Anti-NCSTN
Anti-NCSTN

Item number: G-CAB14505.100

WB 1:500 - 1:2000. Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335)....
Keywords: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, NCSTN Polyclonal Antibody (CAB14505)
Application: WB
Host: Rabbit
Species reactivity: mouse, rat
From 352.00€ *
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Anti-NCSTN
Anti-NCSTN

Item number: G-CAB17111.100

Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546,...
Keywords: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin, NCSTN Rabbit pAb
Application: WB, IHC
Host: Rabbit
Species reactivity: human, mouse
From 352.00€ *
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Anti-NCSTN
Anti-NCSTN

Item number: ATA-HPA054846.100

Protein function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335, PubMed:30598546,...
Keywords: Anti-NCSTN, Anti-KIAA0253, Anti-Nicastrin
Application: IHC
Host: Rabbit
Species reactivity: human
From 300.00€ *
Review
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