Anti-Neurofilament 200 (Heavy), clone N52

Anti-Neurofilament 200 (Heavy), clone N52
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R30062 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS.... more
Product information "Anti-Neurofilament 200 (Heavy), clone N52"
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS. Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68kD (NFL), 125kD (NFM), and 200kD (NFH) on SDS-gel electrophoresis. It is thought that phosphorylation of NFH results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. Genomic clones for the largest human neurofilament protein were isolated, the intron/exon boundaries mapped and the entire protein-coding regions (exons) sequenced. Mutations in neurofilaments have been linked to some forms of Charcot-Marie-Tooth disease(CMT). Protein function: Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. [The UniProt Consortium]
Keywords: Anti-NF-H, Anti-NEFH, Anti-KIAA0845, Anti-200 kDa neurofilament protein, Anti-Neurofilament triplet H protein, Anti-Neurofilament heavy polypeptide, Neurofilament 200 Antibody (Heavy)
Supplier: NSJ Bioreagents
Supplier-Nr: R30062

Properties

Application: WB, IHC (paraffin), IF
Antibody Type: Monoclonal
Clone: N52
Conjugate: No
Host: Mouse
Species reactivity: human, mouse, rat
Immunogen: C-terminal segment of enzymatically dephosphorylated pig Neurofilament 200 was used as the immunogen for this Neurofilament 200 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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