Anti-Neurofilament (H+L), clone SPM145

Anti-Neurofilament (H+L), clone SPM145
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3101-20UG 20 µg - -

3 - 10 business days

NSJ-V3101-100UG 100 µg - -

3 - 10 business days

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This mAb reacts with a 200kDa and... more
Product information "Anti-Neurofilament (H+L), clone SPM145"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This mAb reacts with a 200kDa and 68kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament. Protein function: Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. [The UniProt Consortium]
Keywords: Anti-NF-H, Anti-NEFH, Anti-KIAA0845, Anti-200 kDa neurofilament protein, Anti-Neurofilament heavy polypeptide, Anti-Neurofilament triplet H protein, Neurofilament (H+L) Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3101-20UG


Application: FC, IHC (paraffin)
Antibody Type: Monoclonal
Clone: SPM145
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse, Rat
Immunogen: Semi-purified human neurofilaments from spinal cord
Format: Purified

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Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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