Anti-NAT10

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-385A-T	10 µl (10 µg)		-		2 - 8 business days*		165.00€
A304-385A	100 µl (100 µg)		-		2 - 8 business days*		586.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs... more

Close menu

Product information "Anti-NAT10"

Protein function: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs (PubMed:25653167). Catalyzes the formation of N(4)-acetylcytidine (ac4C) at positions 1337 and 1842 in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis (PubMed:25653167). Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation (PubMed:25653167). Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division (PubMed:14592445, PubMed:17631499, PubMed:18082603, PubMed:19303003). [The UniProt Consortium]

Keywords:	Anti-ALP, Anti-N-acetyltransferase 10, Anti-RNA cytidine acetyltransferase, Anti-18S rRNA cytosine acetyltransferase
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-385A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: mouse, rat, bovine, dog, panda, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, chinese hamster, cat, african elephant, crab-eating macaque, northern white-cheeked gibbon, small-eared galago)
Immunogen:	synthetic peptide. The epitope recognized by A304-385A-T maps to a region between residue 650 to 700 of human N-acetyltransferase 10 using the numbering given in entry NP_078938.2 (GeneID 55226).
Format:	Antigen Affinity Purified