40 products were found matching "K14521"!
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Remodelin
Item number: Cay17346-1
Progeria is a genetic disorder that results in the appearance of premature aging. Genetically, progeria is characterized by a mutation in lamin A, which results in misshapen cell nuclei and DNA damage. Remodelin is a 2-thiazolylhydrazone derivative that, at 10 µM, improves nuclear architecture, chromatin...
| Keywords: | 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile |
| Application: | NAT10 inhibitor |
| CAS | 949912-58-7 |
| MW: | 282.4 D |
From 73.00€
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Anti-NAT10
Item number: A304-385A-T
Protein function: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs (PubMed:25653167). Catalyzes the formation of N(4)-acetylcytidine (ac4C) at positions 1337 and 1842 in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis...
| Keywords: | Anti-ALP, Anti-N-acetyltransferase 10, Anti-RNA cytidine acetyltransferase, Anti-18S rRNA cytosine acetyltransferase |
| Application: | WB, IP, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 165.00€
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Remodelin (hydrobromide)
Item number: Cay16066-1
Progeria is a genetic disorder that results in the appearance of premature aging. Genetically, progeria is characterized by a mutation in lamin A, which results in misshapen cell nuclei and DNA damage. Remodelin is a 2-thiazolylhydrazone derivative that, at 10 µM, improves nuclear architecture, chromatin...
| Keywords: | 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile, monohydrobromide |
| Application: | NAT10 inhibitor |
| CAS | 1622921-15-6 |
| MW: | 363.3 D |
From 56.00€
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Anti-NAT10 / hALP, Internal
Item number: ARG64216.100
Protein function: Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by...
| Keywords: | Anti-ALP, Anti-NAT10, EC=2.3.1.-, Anti-N-acetyltransferase 10 |
| Application: | ELISA, IHC (paraffin) |
| Host: | Goat |
| Species reactivity: | human |
871.00€
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Anti-ALP
Item number: NSJ-R34641-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Acetyltransferase-like protein, N-acetyltransferase 10, NAT10 Protein function: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs (PubMed:25653167). Catalyzes the...
| Keywords: | Anti-ALP, Anti-N-acetyltransferase 10, Anti-RNA cytidine acetyltransferase, Anti-18S rRNA cytosine acetyltransferase, ALP... |
| Application: | IHC, ELISA (peptide) |
| Host: | Goat |
| Species reactivity: | human |
836.00€
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Anti-NAT10
Item number: E-AB-11420.120
N-acetyltransferase 10 is an enzyme that in humans is encoded by the NAT10 gene. Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the...
| Keywords: | Anti-ALP, Anti-N-acetyltransferase 10, Anti-RNA cytidine acetyltransferase, Anti-18S rRNA cytosine acetyltransferase,... |
| Application: | WB, IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 89.00€
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Anti-NAT10
Item number: ATA-HPA057576.100
Protein function: RNA cytidine acetyltransferase that catalyzes the formation of N(4)-acetylcytidine (ac4C) modification on mRNAs, 18S rRNA and tRNAs (PubMed:25411247, PubMed:25653167, PubMed:30449621). Catalyzes ac4C modification of a broad range of mRNAs, enhancing mRNA stability and translation (PubMed:30449621)....
| Keywords: | Anti-hALP, Anti-N-acetyltransferase 10, Anti-RNA cytidine acetyltransferase, Anti-N-acetyltransferase-like protein,... |
| Application: | ICC |
| Host: | Rabbit |
| Species reactivity: | human |
From 246.00€
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Anti-NAT10
Item number: ATA-HPA071628.100
Protein function: RNA cytidine acetyltransferase that catalyzes the formation of N(4)-acetylcytidine (ac4C) modification on mRNAs, 18S rRNA and tRNAs (PubMed:25411247, PubMed:25653167, PubMed:30449621). Catalyzes ac4C modification of a broad range of mRNAs, enhancing mRNA stability and translation (PubMed:30449621)....
| Keywords: | Anti-hALP, Anti-N-acetyltransferase 10, Anti-RNA cytidine acetyltransferase, Anti-N-acetyltransferase-like protein,... |
| Application: | ICC |
| Host: | Rabbit |
| Species reactivity: | human |
From 369.00€
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Anti-NAT10
Item number: CSB-PA088333.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NAT10. Antigen Species: Human
| Keywords: | Anti-hALP, Anti-N-acetyltransferase 10, Anti-RNA cytidine acetyltransferase, Anti-N-acetyltransferase-like protein,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 167.00€
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Anti-NAT10
Item number: CSB-PA792051.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NAT10. Antigen Species: Human
| Keywords: | Anti-hALP, Anti-N-acetyltransferase 10, Anti-RNA cytidine acetyltransferase, Anti-N-acetyltransferase-like protein,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 167.00€
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Remodelin
Item number: TGM-T3499-100mg
Description: Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10. Target: Histone Acetyltransferase. Smiles: Br.N#Cc1ccc(cc1)-c1csc(NN=C2CCCC2)n1. References: Larrieu D, et al. Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science. 2014 May 2,344(6183):527-32.
| Application: | NAT10 inhibitor |
| CAS | 949912-58-7 |
| MW: | 282.36 D |
From 48.00€
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Remodelin hydrobromide
Item number: TGM-T6133-100mg
Description: Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. Target: Histone Acetyltransferase, RAAS. Smiles: C1CCC(=NNc2nc(cs2)c2ccc(cc2)C#N)C1.Br. References: Larrieu D, et al. Science. 2014, 344(6183), 527-532.
| Keywords: | Remodelin HBR, Remodelin |
| Application: | NAT10 inhibitor |
| CAS | 1622921-15-6 |
| MW: | 363.28 D |
From 49.00€
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