Anti-MTH1, recombinant antibody

Anti-MTH1, recombinant antibody
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-RC-16038.50 50 µl - -

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206.00€
ABS-RC-16038.100 100 µl - -

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295.00€
 
Protein function: Antimutagenic (PubMed:8226881, PubMed:7713500, PubMed:10608900). Plays a... more
Product information "Anti-MTH1, recombinant antibody"
Protein function: Antimutagenic (PubMed:8226881, PubMed:7713500, PubMed:10608900). Plays a redundant role in sanitizing oxidized nucleotide pools, such as 8-oxo-dGTP pools (PubMed:28679043). Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress (PubMed:12857738, PubMed:24695224, PubMed:24695225). Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions (PubMed:8226881, PubMed:10373420, PubMed:10608900, PubMed:11756418, PubMed:12857738, PubMed:16607562, PubMed:24695224, PubMed:24695225, PubMed:26999531, PubMed:28035004). Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8- oxo-GTP and 8-oxo-ATP (PubMed:10373420, PubMed:11139615). Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. [The UniProt Consortium]
Keywords: Anti-NUDT1, Anti-Nudix motif 1, Anti-8-oxo-dGTPase, Anti-2-hydroxy-dATP diphosphatase, Anti-7,8-dihydro-8-oxoguanine triphosphatase, Anti-Nucleoside diphosphate-linked moiety X motif 1
Supplier: Absea
Supplier-Nr: RC-16038

Properties

Application: WB
Antibody Type: Monoclonal
Clone: K01_4J55
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: synthesized peptide derived from human MTH1
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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