Anti-MNK2

Anti-MNK2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG44279.50 50 µl - -

6 - 14 business days*

641.00€
 
Protein function: Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and... more
Product information "Anti-MNK2"
Protein function: Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. Required for mediating PP2A- inhibition-induced EIF4E phosphorylation. Triggers EIF4E shuttling from cytoplasm to nucleus. Isoform 1 displays a high basal kinase activity, but isoform 2 exhibits a very low kinase activity. Acts as a mediator of the suppressive effects of IFNgamma on hematopoiesis. Negative regulator for signals that control generation of arsenic trioxide As(2)O(3)-dependent apoptosis and anti-leukemic responses. Involved in anti-apoptotic signaling in response to serum withdrawal. [The UniProt Consortium]
Keywords: Anti-Mnk2, Anti-Mnk2, Anti-MKNK2, Anti-GPRK7, Anti-MAPK signal-integrating kinase 2, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating kinase 2, Anti-MAP kinase signal-integrating kinase 2, Anti-MAP kinase-interacting serine/threon
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG44279

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: primates)
Immunogen: MNK2A synthetic peptide
MW: 52 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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