68 products were found matching "K04372"!

DS12881479 is an inhibitor of MAP kinase-interacting serine/threonine protein kinase 1 (MNK1, IC50s = 21 and 416 nM for the inactive and active forms, respectively). It is selective for MNK1 over 46 other kinases but does inhibit FMS-related tyrosine kinase 3 (FLT3) and dual-specificity tyrosine...

Rabbit Polyclonal MKNK1 Antibody against Human MAPK interacting serine/threonine kinase 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000028708: 84%,...

CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1) in vitro (IC50 = 2.2 µM), with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases. It blocks the phosphorylation of eIF4E in response to TNF-alpha, arsenite, anisomycin, PMA, or fetal calf serum in 293 cells (IC50 =...

Active human MNK (T385D, amino acids 2nd-End (deletion 165-205aa)) (GenBank Accession No. NM_003684), with N-terminal GST tag, MW=74 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Recombinant human MNK2 (MAP kinase interacting serine/threonine kinase 2), also known as GPRK7 (G protein-coupled receptor kinase 7), GenBank Accession No. NM_017572, full length, with N-terminal GST tag, MW ~74 kDa, expressed in Sf9 insect cells via a baculovirus expression system.

Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity). Applications: Suitable for use in Western Blot, ELISA, Recommended...

The MNK1 Kinase Assay Kit is designed to measure MNK1 kinase activity for screening and profiling applications using ADP-Glo(R) Kinase Assay as a detection reagent.

MKNK2 Antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in ELISA, WB applications. MKNK2 Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the...

Protein function: Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA...

Protein function: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine- containing mRNA cap. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium...

Protein function: Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-465aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MVSSQKLEKP IEMGSSEPLP IADGDRRRKK KRRGRATDSL PGKFEDMYKL TSELLGEGAY AKVQGAVSLQ NGKEYAVKII EKQAGHSRSR VFREVETLYQ CQGNKNILEL IEFFEDDTRF YLVFEKLQGG...