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Protein function: Component of the Mediator complex, a coactivator involved in the regulated... more
Product information "Anti-MED15"
Protein function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway. [The UniProt Consortium]
Keywords: | Anti-TIG-1, Anti-MED15, Anti-ARC105, Anti-CTG repeat protein 7a, Anti-Mediator complex subunit 15, Anti-TPA-inducible gene 1 protein, Anti-PC2 glutamine/Q-rich-associated protein, Anti-Activator-recruited cofactor 105 kDa component |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A302-423A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Reactivity: | Human (Expected: Mouse) |
Immunogen: | synthetic peptide. The epitope recognized by A302-423A-T maps to a region between residue 650 and 700 of human mediator complex subunit 15 using the numbering given in entry NP_001003891.1 (GeneID 51586). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K15157 | Find alternatives |
UniProt ID : | Q96RN5 | Find alternatives |
Gene ID | GeneID 51586 | Find alternatives |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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