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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R32948 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Mediator of RNA polymerase II... more
Product information "Anti-MED15 / PCQAP"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Mediator of RNA polymerase II transcription subunit 15, also known as Gal11, Spt13 in yeast and PCQAP, ARC105, or TIG-1 in humans is a protein encoded by the MED15 gene. The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome. Protein function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol- dependent gene regulation. Positively regulates the Nodal signaling pathway. [The UniProt Consortium]
Keywords: | Anti-TIG-1, Anti-MED15, Anti-ARC105, Anti-CTG repeat protein 7a, Anti-Mediator complex subunit 15, Anti-TPA-inducible gene 1 protein, Anti-PC2 glutamine/Q-rich-associated protein, Anti-Trinucleotide repeat-containing gene 7 protein, MED15 Antibody / PCQAP |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R32948 |
Properties
Application: | WB, IHC (paraffin), FC, IF, Direct ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | A recombinant human protein corresponding to amino acids M1-A285 |
Format: | Purified |
Database Information
KEGG ID : | K15157 | Matching products |
UniProt ID : | Q96RN5 | Matching products |
Gene ID | GeneID 51586 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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