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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG10721.50 | 50 µl | - | - |
6 - 14 business days* |
551.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or... more
Product information "Anti-MBNL1, clone 1H1"
Protein function: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y- 3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues. [The UniProt Consortium]
| Keywords: | Anti-EXP, Anti-MBNL1, Anti-Muscleblind-like protein 1, Anti-Triplet-expansion RNA-binding protein |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG10721 |
Properties
| Application: | WB, ICC, IF, IHC (frozen) |
| Antibody Type: | Monoclonal |
| Clone: | 1H1 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human, horse, cow, swine, rat, mouse (Expected: chicken) |
| Immunogen: | Full-length recombinant Human MBNL1 |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K14943 | Matching products |
| UniProt ID : | Q9NR56 | Matching products |
| Gene ID : | GeneID 4154 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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