Anti-MBNL1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55342.100	100 µl		-	-	6 - 14 business days*		707.00€

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Protein function: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or... more

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Product information "Anti-MBNL1"

Protein function: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y- 3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues. [The UniProt Consortium]

Keywords:	Anti-EXP, Anti-MBNL1, Anti-Muscleblind-like protein 1, Anti-Triplet-expansion RNA-binding protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55342

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide of Human MBNL1
MW:	41 kD
Format:	Antigen Affinity Purified