Anti-LTB4R

LTB4R (Leukotriene B4 Receptor) is a Protein Coding gene. Diseases associated with LTB4R include Cicatricial Entropion and Spastic Entropion. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and leukotriene receptor activity. An important paralog of this gene is LTB4R2. Protein function: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. [The UniProt Consortium]