Anti-LSD1+8a (human), Rabbit Monoclonal (RM523)

Anti-LSD1+8a (human), Rabbit Monoclonal (RM523)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
REV-31-1415-00-R100 100 µl - -

3 - 9 business days*

541.00€
 
LSD1+8a (Lysine-Specific Demethylase 1 isoform 8a) is an alternatively spliced variant of the... more
Product information "Anti-LSD1+8a (human), Rabbit Monoclonal (RM523)"
LSD1+8a (Lysine-Specific Demethylase 1 isoform 8a) is an alternatively spliced variant of the LSD1 (KDM1A) gene that includes the neuron-specific exon 8a. This isoform is predominantly expressed in the brain and plays a key role in neuronal differentiation and function. While canonical LSD1 regulates gene expression by demethylating histone H3 on lysine 4 (H3K4me1/2), the +8a variant shows altered substrate specificity and interacts with different cofactors, contributing to neuron-specific transcriptional programs. Dysregulation of LSD1+8a has been implicated in neurodevelopmental disorders and certain cancers.
Keywords: Anti-KDM1A, Anti-BRAF35-HDAC complex protein BHC110, Anti-Lysine-specific histone demethylase 1A, Anti-Flavin-containing amine oxidase domain-containing protein 2, Anti-[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A
Supplier: RevMAb Biosciences
Supplier-Nr: 31-1415-00

Properties

Application: IHC, WB
Antibody Type: Monoclonal
Clone: RM523
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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