Anti-LMP7, C-terminal

Anti-LMP7, C-terminal
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG64947.100 100 µg - -

6 - 14 business days*

784.00€
 
Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by... more
Product information "Anti-LMP7, C-terminal"
Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB5 by PSMB8 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Acts as a major component of interferon gamma-induced sensitivity. Plays a key role in apoptosis via the degradation of the apoptotic inhibitor MCL1. May be involved in the inflammatory response pathway. In cancer cells, substitution of isoform 1 (E2) by isoform 2 (E1) results in immunoproteasome deficiency. Required for the differentiation of preadipocytes into adipocytes. [The UniProt Consortium]
Keywords: Anti-LMP7, Anti-PSMB8, EC=3.4.25.1, Anti-Macropain subunit C13, Anti-Proteasome component C13, Anti-Proteasome subunit beta-5i, Anti-Low molecular mass protein 7, Anti-Proteasome subunit beta type-8, Anti-Really interesting new gene 10 protein
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG64947

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: human (Expected: mouse, rat, canine, swine, bovine)
Immunogen: C-DVSDLLHQYREANQ
Format: Ammonium Sulfate Precipitated

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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