Anti-PSMB8, NT (PSMB8, LMP7, PSMB5i, RING10, Y2, Proteasome subunit beta type-8, Low molecular mass

Anti-PSMB8, NT (PSMB8, LMP7, PSMB5i, RING10, Y2, Proteasome subunit beta type-8, Low molecular mass
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040559.200 200 µl - -

1 - 19 business days

557.00€
 
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core... more
Product information "Anti-PSMB8, NT (PSMB8, LMP7, PSMB5i, RING10, Y2, Proteasome subunit beta type-8, Low molecular mass"
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified, both isoforms are processed to yield the same mature subunit. Applications: Suitable for use in Western Blot, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000, Flow Cytometry: 1:10-1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-LMP7, Anti-PSMB8, EC=3.4.25.1, Anti-Macropain subunit C13, Anti-Proteasome component C13, Anti-Proteasome subunit beta-5i, Anti-Low molecular mass protein 7, Anti-Proteasome subunit beta type-8, Anti-Really interesting new gene 10 protein
Supplier: United States Biological
Supplier-Nr: 040559

Properties

Application: ELISA, FC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: PSMB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human PSMB8.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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