Anti-LIMK2

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA008183.25 25 µl -

7 - 10 business days*

330.00€
ATA-HPA008183.100 100 µl -

7 - 10 business days*

463.00€
 
Protein function: Serine/threonine-protein kinase that plays an essential role in the regulation... more
Product information "Anti-LIMK2"
Protein function: Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics (PubMed:10436159, PubMed:11018042). Acts downstream of several Rho family GTPase signal transduction pathways (PubMed:10436159, PubMed:11018042). Involved in astral microtubule organization and mitotic spindle orientation during early stages of mitosis by mediating phosphorylation of TPPP (PubMed:22328514). Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro (PubMed:8537403). Suppresses ciliogenesis via multiple pathways, phosphorylation of CFL1, suppression of directional trafficking of ciliary vesicles to the ciliary base, and by facilitating YAP1 nuclear localization where it acts as a transcriptional corepressor of the TEAD4 target genes AURKA and PLK1 (PubMed:25849865). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 90% and to rat: 88%
Keywords: Anti-LIMK2, Anti-LIMK-2, Anti-LIM domain kinase 2
Supplier: Atlas Antibodies
Supplier-Nr: HPA008183

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: VEEVEDAISQ TSQTLQLLIE HDPVSQRLDQ LRLEARLAPH MQNAGHPHAL STLDTKENLE GTLRRRSLRR SNSISKSPGP SSPKEPLLFS RDISRSESLR CSSSYSQ (ATA-APrEST71462)

Database Information

KEGG ID : K05744 | Matching products
UniProt ID : P53671 | Matching products
Gene ID : GeneID 3985 | Matching products
Protein Atlas Nr. : ENSG00000182541

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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