31 products were found matching "K05744"!

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TH263
TH263

Item number: Cay37295-5

TH263 is an inactive analog of the inhibitor of LIM kinase 1 (LIMK1) and LIMK2 TH257 (Cay-34236) that has been used as a negative control for the kinase activity of LIMK1 and LIMK2.Formal Name: N-(phenylmethyl)-4-[[(phenylmethyl)amino]sulfonyl]-benzamide. CAS Number: 313520-94-4. Molecular Formula: C21H20N2O3S....
Keywords: N-(phenylmethyl)-4-[[(phenylmethyl)amino]sulfonyl]-benzamide
Application: TH257 inactive kinase inhibitor analog, control
CAS 313520-94-4
MW: 380.5 D
From 117.00€ *
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BMS-5
BMS-5

Item number: SYN-1024-M001

Soluble in DMSO. Kinases, such as LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2), have been identified as participating in signal pathways affecting actin dynamics by deactivating cofilin. Over expression of LMK1 has been found in invasive breast and prostate cancer cell lines and suppression of LIMK 2 expression has...
Keywords: BMS5
Application: LIMK1 / LIMK2 inhibitor
CAS 1338247-35-0
MW: 431,3 D
From 106.00€ *
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-10 %
BMS-3
BMS-3

Item number: AG-CR1-2901-M005

Off-white solid. Soluble in DMSO (5mg/ml). Potent LIMK (Lim kinase) inhibitor. Has IC50 values of 5nM and 6nM for LIMK1 and LIMK2, respectively.
Keywords: N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2- yl)cyclopropanecarboxamide
Application: Potent LIMK inhibitor
CAS 1338247-30-5
MW: 429,3 D
88.00€ * From 79.20€ *
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BMS-5
BMS-5

Item number: Cay21072-1

BMS-5 is a potent inhibitor of activated LIM domain kinases LIMK1 and LIMK2 with IC50 values of 7 and 8 nM, respectively. LIMK1 and LIMK2 participate in signal pathways affecting actin dynamics by deactivating cofilin. This compound can be used to study the role of activated LIMK isoforms in the signaling of Rho...
Keywords: LIM Kinase Inhibitor I, LIMKi 3,...
Application: LIMK1 / LIMK2 inhibitor
CAS 1338247-35-0
MW: 431.3 D
From 65.00€ *
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Anti-LIMK2
Anti-LIMK2

Item number: ARG55700.100

Protein function: Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro. [The UniProt Consortium]
Keywords: Anti-LIMK2, Anti-LIMK-2, EC=2.7.11.1, Anti-LIM domain kinase 2
Application: WB
Host: Rabbit
Species reactivity: human
584.00€ *
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Anti-LIM Kinase 2 / LIMK2
Anti-LIM Kinase 2 / LIMK2

Item number: NSJ-R32136

0.5mg/ml if reconstituted with 0.2ml sterile DI water. LIM domain kinase 2 is an enzyme that in humans is encoded by the LIMK2 gene. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc...
Keywords: Anti-LIMK2, Anti-LIMK-2, EC=2.7.11.1, Anti-LIM domain kinase 2, LIM Kinase 2 Antibody / LIMK2
Application: WB
Host: Rabbit
Species reactivity: human, mouse
755.00€ *
Review
BMS-3
BMS-3

Item number: Cay19421-1

BMS-3 is a potent inhibitor of activated LIM domain kinases LIMK1 and LIMK2 (IC50s = 5 and 6 nM, respectively). It is used to study the role of activated LIMK isoforms in the signaling of Rho family GTPases to cytoskeletal proteins, including cofilin and tubulin.Formal Name:...
Keywords: N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-cyclopropanecarboxamide
Application: LIMK1 / LIMK2 inhibitor
CAS 1338247-30-5
MW: 429.3 D
From 43.00€ *
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LX7101 (hydrochloride)
LX7101 (hydrochloride)

Item number: Cay21209-1

LX7101 is a potent inhibitor of LIM kinase (LIMK) 1 and 2 and Rho-associated kinase 1 (ROCK1) and ROCK2 with IC50 values of 32, 4.3, 69, and 32 nM, respectively. It is selective, showing no cross reactivity in a panel of binding assays including 78 receptors and transporters and 430 additional kinases, at a...
Keywords: N,N-dimethyl-carbamic acid,...
Application: LIMK2 inhibitor
CAS 2319882-48-7
MW: 488 D
From 90.00€ *
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T5601640
T5601640

Item number: Cay22140-1

T5601640 is an inhibitor of LIM kinase 2 (LIMK2) that inhibits LIMK2-mediated cofilin phosphorylation. It reduces the levels of phosphorylated cofilin (p-cofilin) in mouse embryonic fibroblasts (MEF) lacking neurofibromin (Nf1-/-, IC50 = 30 µM), which normally have high levels of p-cofilin. T5601640 (50 µM)...
Keywords: T56-LIM Kinase Inhibito, T56-LIMKi, 3-methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide
Application: LIMK2 inhibitor
CAS 924473-59-6
MW: 389.3 D
From 43.00€ *
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Anti-phospho-LIMK2 (Thr505)
Anti-phospho-LIMK2 (Thr505)

Item number: ABE-35-1123-50

Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro. Protein function: Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics (PubMed:10436159, PubMed:11018042). Acts downstream of several Rho family GTPase signal...
Keywords: Anti-phospho-LIMK2, Anti-phospho-LIMK-2, Anti-phospho-LIM domain kinase 2, Polyclonal Antibody to LIMK2 (Phospho-Thr505)
Application: WB, IHC, IF
Host: Rabbit
Species reactivity: human, mouse, rat
574.00€ *
Review
Anti-phospho-LIMK2 (Thr505)
Anti-phospho-LIMK2 (Thr505)

Item number: ABE-35-1123-100

Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro. Protein function: Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro. [The UniProt Consortium]
Keywords: Anti-phospho-LIMK2, Anti-phospho-LIMK-2, EC=2.7.11.1, Anti-phospho-LIM domain kinase 2, Polyclonal Antibody to LIMK2...
Application: WB, IHC, IF
Host: Rabbit
Species reactivity: human, mouse, rat
682.00€ *
Review
LIMK1/2 (Phospho-Thr505) Colorimetric Cell-Based ELISA Kit
LIMK1/2 (Phospho-Thr505) Colorimetric Cell-Based ELISA Kit

Item number: G-CBCAB01561.96

LIMK1/2 (Phospho-Thr505) Colorimetric Cell-Based ELISA Kit Protein function: Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics (PubMed:10436159, PubMed:11018042). Acts downstream of several Rho family GTPase signal transduction pathways (PubMed:10436159,...
Keywords: LIMK2, LIMK-2, LIM domain kinase 2
Application: In-cell ELISA
641.00€ *
Review
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